Recent advances in activity-based probes (ABPs) and affinity-based probes (A<i>f</i>BPs) for profiling of enzymes
Haixiao Fang, Bo Peng, Sing Yee Ong, Qiong Wu, Lin Li, Shao Q. Yao
Abstract
This review highlights the recent advances in the use of activity-based probes (ABPs) and affinity-based probes (A<italic>f</italic>BPs), and summarizes their design strategies (based on inhibitors and substrates) and detection approaches.
Topics & Concepts
Computational biologyProfiling (computer programming)ChemistryEnzymeCombinatorial chemistryBiochemistryNanotechnologyBiologyComputer scienceMaterials scienceOperating systemClick Chemistry and ApplicationsChemical Synthesis and AnalysisAdvanced biosensing and bioanalysis techniques