Single-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier dysfunction in checkpoint inhibitor colitis
Molly Thomas, Kamil Slowikowski, Kasidet Manakongtreecheep, Pritha Sen, Nandini Samanta, Jessica Tantivit, Mazen Nasrallah, Leyre Zubiri, Neal P. Smith, Alice Tirard, Swetha Ramesh, Benjamin Y. Arnold, Linda T. Nieman, Jonathan Chen, Thomas Eisenhaure, Karin Pelka, Yuhui Song, Katherine Xu, Vjola Jorgji, Christopher J. Pinto, Tatyana Sharova, Rachel Glasser, PuiYee Chan, Ryan J. Sullivan, Hamed Khalili, Dejan Juric, Genevieve M. Boland, Michael Dougan, Nir Hacohen, Bo Li, Kerry L. Reynolds, Alexandra–Chloé Villani
Topics & Concepts
TranscriptomeColitisImmune systemBiologyCellCancer researchCell biologyImmunologyGeneGene expressionGeneticsImmune Cell Function and InteractionCancer Immunotherapy and BiomarkersMicroscopic Colitis