Polysaccharides from natural <i>Cordyceps sinensis</i> attenuated dextran sodium sulfate-induced colitis in C57BL/6J mice
Shuping Chen, Junqiao Wang, Nan Dong, Qiuyue Fang, Yanli Zhang, Chunhua Chen, Steve W. Cui, Shaoping Nie
Abstract
As potential candidates for treating ulcerative colitis (UC), polysaccharides from natural Cordyceps sinensis inhibited the activation of the NF-κB pathway, enhanced the intestinal barrier, increased the content of sIgA and modulated the gut microbiota in colitis mice.
Topics & Concepts
PolysaccharideCordycepsColitisOccludinChemistryDextranMicrobiologyImmunologyBiochemistryBiologyFood scienceTight junctionGut microbiota and healthFungal Biology and ApplicationsPolysaccharides and Plant Cell Walls