Litcius/Paper detail

Oropharyngeal capsaicin exposure improves infant feeding performance in an animal model of superior laryngeal nerve damage

Chloe E. Edmonds, Rebecca Z. German, Laura E. Bond, Christopher J. Mayerl

2022Journal of Neurophysiology16 citationsDOIOpen Access PDF

Abstract

Chemical sensory interventions alter swallow physiology, which is well-documented in adults but relatively unexplored in infants. Using videofluoroscopy, we found that capsaicin exposure limited infant pigs' bolus sizes to improve swallow performance without changing swallow frequency. Capsaicin increased the likelihood of safe swallowing with more moderately sized boluses and changed relationships between bolus size and tongue movements, which may impact performance. This work highlights the potential role of capsaicin in treating acute infant dysphagia.

Topics & Concepts

CapsaicinNeuroscienceSuperior laryngeal nerveAnimal modelMedicineAnesthesiaPsychologyStimulationInternal medicineReceptorNeuroscience of respiration and sleepDysphagia Assessment and ManagementInfant Health and Development