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Hypertrophic Cardiomyopathy ― A Heterogeneous and Lifelong Disease in the Real World ―

Hiroaki Kitaoka, Toru Kubo, Yoshinori Doi

2020Circulation Journal28 citationsDOIOpen Access PDF

Abstract

Hypertrophic cardiomyopathy (HCM) is the most frequent hereditary cardiomyopathy, showing an autosomal-dominant f inheritance. A great deal of attention has been paid to genetics, left ventricular tract obstruction and the prediction and prevention of sudden cardiac death in HCM. Needless to say, these are very important, but we should recognize the heterogeneity in etiology, morphology, clinical course and management of this unique cardiomyopathy. Another important perspective is that HCM causes left ventricular remodeling over time and is a disease that requires lifelong management in the real world.

Topics & Concepts

Hypertrophic cardiomyopathyCardiologyCardiomyopathyMedicineEtiologyDiseaseInternal medicineRestrictive cardiomyopathySudden deathHeart failureCardiomyopathy and Myosin StudiesCardiovascular Function and Risk FactorsTrypanosoma species research and implications
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