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Antidepressant-like Effect of 3-n-Butylphthalide in Rats Exposed to Chronic Unpredictable Mild Stress: Modulation of Brain-Derived Neurotrophic Factor Level and mTOR Activation in Cortex

Chunlin Chen, Hao Ma, Zhifeng Fu

2021Neurochemical Research17 citationsDOI

Topics & Concepts

AntidepressantTail suspension testNeurotrophic factorsEndocrinologyMAPK/ERK pathwaySynapsin IPI3K/AKT/mTOR pathwayPharmacologyInternal medicineChronic stressBehavioural despair testBrain-derived neurotrophic factorFluoxetinePrefrontal cortexChemistryMedicineHippocampusNeurosciencePsychologySerotoninPhosphorylationSignal transductionReceptorBiochemistrySynaptic vesicleVesicleCognitionMembraneNeurological Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration MechanismsMorinda citrifolia extract uses
Antidepressant-like Effect of 3-n-Butylphthalide in Rats Exposed to Chronic Unpredictable Mild Stress: Modulation of Brain-Derived Neurotrophic Factor Level and mTOR Activation in Cortex | Litcius