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Enzalutamide-induced and PTH1R-mediated TGFBR2 degradation in osteoblasts confers resistance in prostate cancer bone metastases

Shang Su, Jingchen Cao, Xiangqi Meng, Ruihua Liu, Alexandra Vander Ark, Erica Woodford, Reian Zhang, Isabelle Stiver, Xiaotun Zhang, Zachary Madaj, Megan J. Bowman, Yingying Wu, H. Eric Xu, Bin Chen, Haiquan Yu, Xiaohong Li

2021Cancer Letters20 citationsDOIOpen Access PDF

Topics & Concepts

EnzalutamideProstate cancerOsteoblastCancer researchTumor microenvironmentMedicineCancerChemistryInternal medicineIn vitroTumor cellsAndrogen receptorBiochemistryProstate Cancer Treatment and ResearchBone health and treatmentsCancer-related Molecular Pathways
Enzalutamide-induced and PTH1R-mediated TGFBR2 degradation in osteoblasts confers resistance in prostate cancer bone metastases | Litcius