E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis
Jay V. Patankar, Tanja M. Müller, Srinivas Kantham, Miguel Gonzalez Acera, Fabrizio Mascia, Kristina Scheibe, Mousumi Mahapatro, Christina Heichler, Yuqiang Yu, Wei Li, Barbara Ruder, Claudia Günther, Moritz Leppkes, Mano Joseph Mathew, Stefan Wirtz, Clemens Neufert, Anja A. Kühl, Jay Paquette, Kevan Jacobson, Raja Atreya, Sebastian Zundler, Markus F. Neurath, Robert N. Young, Christoph Becker
Topics & Concepts
NecroptosisCell biologyInflammationBiologyRIPK1Signal transductionKinaseProgrammed cell deathTumor necrosis factor alphaReceptorImmunologyApoptosisBiochemistryImmune Response and InflammationNF-κB Signaling PathwaysCell death mechanisms and regulation