Dual-Polymeric Resin Based on Poly(methyl vinyl ether-<i>alt</i>-maleic anhydride) and PAMAM Dendrimer as a Versatile Supramolecular Adsorbent
Mateusz Pawlaczyk, Grzegorz Schroeder
Abstract
Adsorptive materials demand meeting several criteria, including the versatility of applications, synthetic easiness, reusability, eco-friendliness, and low-cost production. Therefore, the following study aimed at the synthesis of dual-polymeric material containing biocompatible poly(methyl vinyl ether−alt−maleic anhydride) (PMVEAMA) matrix functionalized with multifunctional and branched poly(amidoamine) (PAMAM) dendrimer. The obtained PMVEAMA−PAMAM material was characterized with several analytical techniques and investigated as an adsorbent of several analytes, which belong to a class of either water contaminants or bioactive molecules. Adsorption isothermal studies have been performed, using aqueous solutions of analytes (conditions: distilled water or phosphate buffer pH 8.0 solutions of concentration ranging between 0.1 and 1 mM; room temperature; 24 h incubation), which revealed highly satisfactory results of the maximal adsorption capacity qm values, e.g. 367.65 and 304.88 mg g–1 for Congo Red and folic acid, respectively. The studies aiming to a description of the material–dye complexes included also adsorption kinetic studies and 5 cycles of adsorption/desorption steps, showing fast and intense dye adsorption and high reusability of the material toward dye scavenging. Moreover, PMVEAMA−PAMAM has been investigated for the drug delivery of four biocompounds. The release studies performed in three different media showed that material–drug complexes dissociate to the highest extent at pH 2.0, reaching maximally 94.90% for salicylic acid. The performed experiments indicate the versatility of PMVEAMA−PAMAM applications, including chemical analysis, environmental protection, and in vitro biomedical application.