Quality of CD8 <sup>+</sup> T cell immunity evoked in lymph nodes is compartmentalized by route of antigen transport and functional in tumor context
Meghan J. O’Melia, Nathan A. Rohner, Margaret P. Manspeaker, David M. Francis, Haydn Kissick, Susan N. Thomas
Abstract
Nanoscale biomaterial tools reveal impacts of lymphatic mechanisms of transport on CD8 + T cell immunity elicited in melanoma.
Topics & Concepts
Context (archaeology)ImmunityLymphatic systemLymphCD8BiologyAntigenImmunologyCell biologyNeuroscienceImmune systemMedicinePathologyPaleontologyImmunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersCAR-T cell therapy research