A convenient detection system consisting of efficient Au@PtRu nanozymes and alcohol oxidase for highly sensitive alcohol biosensing
Feng Lv, Yuzhu Gong, Yingying Cao, Yaoyao Deng, Shufeng Liang, Xin Tian, Hongwei Gu, Jun‐Jie Yin
Abstract
formed by the oxidation of alcohol to acetaldehyde in the presence of AOx. When coupled with AOx, alcohol was detected down to 23.8 μM in a buffer solution for biological assays. Notably, alcohol was successfully detected in mouse blood samples with results comparable to that from commercial alcohol meters. These results highlight the potential of the Au@PtRu nanorods with peroxidase-like activity for alcohol detection, which opens up a new avenue for nanozyme development for biomedical applications.
Topics & Concepts
Alcohol oxidaseAlcoholAcetaldehydeAlcohol oxidationNanorodBiosensorContext (archaeology)ChemistryNanomaterialsCatalysisNanotechnologyEthanolPeroxidaseMaterials scienceBiochemistryEnzymeBiologyRecombinant DNAGenePaleontologyPichia pastorisAdvanced Nanomaterials in CatalysisElectrochemical sensors and biosensorsBiosensors and Analytical Detection