Elucidating the Regulatory Elements for Transcription Termination and Posttranscriptional Processing in the Streptomyces clavuligerus Genome
Soonkyu Hwang, Namil Lee, Donghui Choe, Yongjae Lee, Woori Kim, Yujin Jeong, Suhyung Cho, Bernhard Ø. Palsson, Byung‐Kwan Cho
Abstract
Streptomyces sp. is a great source of bioactive secondary metabolites, including antibiotics, antifungal agents, antiparasitic agents, immunosuppressant compounds, and other drugs. Secondary metabolites are synthesized via multistep conversions of the precursor molecules from primary metabolism, governed by multicomplex enzymes from secondary metabolite biosynthetic gene clusters.
Topics & Concepts
Streptomyces clavuligerusTranscription (linguistics)GenomeStreptomycesComputational biologyGeneticsBiologyGeneBacteriaActinomycetalesPhilosophyLinguisticsMicrobial Natural Products and BiosynthesisRNA and protein synthesis mechanismsGenomics and Phylogenetic Studies