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Inhibition of histone demethylase KDM4 by ML324 induces apoptosis through the unfolded protein response and Bim upregulation in hepatocellular carcinoma cells

So Young Kim, Supyong Hwang, Bora Lee, Jung Ae Hong, Young Hoon Sung, Inki Kim

2022Chemico-Biological Interactions23 citationsDOI

Topics & Concepts

Unfolded protein responseDemethylaseCancer researchBiologyProgrammed cell deathApoptosisHistoneCell biologyGeneBiochemistryEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and TherapyHistone Deacetylase Inhibitors Research
Inhibition of histone demethylase KDM4 by ML324 induces apoptosis through the unfolded protein response and Bim upregulation in hepatocellular carcinoma cells | Litcius