Dearomative Michael addition involving enals and 2-nitrobenzofurans realized under NHC-catalysis
Mateusz Dyguda, Anna Skrzyńska, Lesław Sieroń, Łukasz Albrecht
Abstract
addition of homoenolate to Michael acceptors leading to the formation of biologically important heterocycles with high yields and stereoselectivities. Their functionalization potential has been confirmed in selected, diastereoselective transformations.
Topics & Concepts
Michael reactionCarbeneEnantioselective synthesisCatalysisChemistrySurface modificationOrganocatalysisCombinatorial chemistryOrganic chemistryPhysical chemistryN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsAsymmetric Hydrogenation and Catalysis