The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis
Kristiana Salmon, Matthew C. Kiernan, Seung Hyun Kim, Peter M. Andersen, Adriano Chiò, Leonard H. van den Berg, Philip Van Damme, Ammar Al‐Chalabi, Patricia Lillo, Jinsy Andrews, Angela Genge
Abstract
Several genetically-targeted therapies are being developed for ALS. Research is increasingly supportive of a greater incidence of clinically actionable variants in sporadic ALS than previously reported. Salmon et al. outline the need to improve access, and offer genetic testing to all people diagnosed with ALS.
Topics & Concepts
Amyotrophic lateral sclerosisGenetic testingMedicineIncidence (geometry)PsychologyDiseasePathologyInternal medicineOpticsPhysicsAmyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research