Challenges in the implementation of ultrasensitive liquid biopsy approaches in precision oncology
Aakash Desai, Christine M. Lovly
Abstract
Cell-free DNA (cfDNA) is DNA present in the cell-free component of blood (plasma and serum) or other human bodily fluids.[1][1] In patients diagnosed with cancer, a component of this cfDNA includes tumor-derived DNA arising from primary or metastatic cancer sites, also known as circulating tumor DNA
Topics & Concepts
Liquid biopsyCell-free fetal DNADNAPrecision oncologyBiopsyMedicineCirculating tumor cellCirculating tumor DNAComponent (thermodynamics)OncologyCancerInternal medicineCancer researchPathologyComputational biologyBiologyMetastasisGeneticsPrenatal diagnosisThermodynamicsPregnancyPhysicsFetusCancer Genomics and DiagnosticsRenal cell carcinoma treatmentPancreatic and Hepatic Oncology Research