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Inducible regulating homologous recombination enables precise genome editing in Pichia pastoris without perturbing cellular fitness

Fan Bai, Peng Cai, Lun Yao, Yiwei Shen, Yunxia Li, Yongjin J. Zhou

2025Trends in biotechnology13 citationsDOI

Topics & Concepts

Pichia pastorisGenome editingHomologous recombinationCRISPRBiologyTetRGenePichiaCas9Computational biologyGeneticsRepressorGene expressionRecombinant DNACRISPR and Genetic EngineeringViral Infectious Diseases and Gene Expression in InsectsFungal and yeast genetics research
Inducible regulating homologous recombination enables precise genome editing in Pichia pastoris without perturbing cellular fitness | Litcius