Conduit arterial wave reflection promotes pressure transmission but impedes hydraulic energy transmission to the microvasculature
Avinash Kondiboyina, Joseph J. Smolich, Michael M.H. Cheung, Berend E. Westerhof, Jonathan P. Mynard
Abstract
With aging, a reduction in the stiffness gradient between elastic and muscular arteries is thought to reduce wave reflection in conduit arteries, leading to increased pulsatile pressure transmission into the microvasculature. This assumes that wave reflection limits pressure transmission in arteries. However, using a computational model, we showed that wave reflection promotes pulsatile pressure transmission, although it does limit hydraulic energy transmission. Increased microvascular pulse pressure with aging is instead related to decreasing arterial compliance.
Topics & Concepts
Pulsatile flowReflection (computer programming)Electrical conduitArterial stiffnessTransmission (telecommunications)Compliance (psychology)Materials sciencePulse pressureBlood pressureCardiologyOpticsMedicineInternal medicinePhysicsComputer scienceElectrical engineeringEngineeringProgramming languagePsychologySocial psychologyCardiovascular Health and Disease PreventionOptical Imaging and Spectroscopy TechniquesNon-Invasive Vital Sign Monitoring