Cell-free DNA tissues of origin by methylation profiling reveals significant cell, tissue, and organ-specific injury related to COVID-19 severity
Alexandre Pellan Cheng, Matthew P. Cheng, Wei Gu, Joan Sesing Lenz, Elaine Hsu, Erwin Schurr, Guillaume Bourque, Mathieu Bourgey, Jerome Ritz, Francisco M. Marty, Charles Y. Chiu, Donald C. Vinh, Iwijn De Vlaminck
Topics & Concepts
DNA methylationCoronavirus disease 2019 (COVID-19)Cell-free fetal DNACellMedicineProgenitor cellDiseaseInternal medicineBiologyImmunologyPathologyBioinformaticsStem cellInfectious disease (medical specialty)GeneticsGeneGene expressionFetusPregnancyPrenatal diagnosisCancer Genomics and DiagnosticsEpigenetics and DNA MethylationSingle-cell and spatial transcriptomics