Mycoplasma bovis<i>mbfN</i>Encodes a Novel LRR Lipoprotein That Undergoes Proteolytic Processing and Binds Host Extracellular Matrix Components
J. Adamu, Filimon Mitiku, Carol A. Hartley, Fiona M. Sansom, Marc S. Marenda, Philip F. Markham, Glenn F. Browning, Kelly A. Tivendale
Abstract
Experimental validation of the putative functions of genes in M. bovis will advance our understanding of the basic biology of this economically important pathogen and is crucial in developing prevention strategies. This study demonstrated the extracellular matrix binding ability of a novel immunogenic lipoprotein of M. bovis , and the role of this protein in adhesion by M. bovis suggests that it could play a role in virulence.
Topics & Concepts
BiologyExtracellular matrixExtracellularMycoplasmaMicrobiologyGeneticsCell biologyMicrobial infections and disease researchAquaculture disease management and microbiotaBacteriophages and microbial interactions