Sarcomas developed in patients with Lynch Syndrome are enriched in pleomorphic soft-tissue sarcomas and are sensitive to immunotherapy
François Poumeaud, Thibaud Valentin, Nadim Farés, Bertille Segier, Sarah Watson, Benjamin Verret, Camille Tlemsani, N. Penel, Stéphanie Lejeune, N. Firmin, Annabelle Sabouret, J. C. Thery, S. Bonvalot, Edouard Cottereau, Estelle Cauchin, Agnès Lançon, Sophie Nambot, Hélène Zattara, Mathieu Coudert, Emmanuelle Fourme, C. Nogues, David Tougeron, Fabienne Prieur, M-A. Collonge-Rame, Colette Denis, P. Laurent-Puig, Stephanie Chieze-Valéro, Hubert L. Dreyfus, Marion Jaffrelot, Pierre Vande Perre, Philippe Rochaix, Anne Gomez‐Mascard, Pauline Rochefort, Silvia Ramos Campoy, Frédéric Chibon, Christine Lasset, Janick Sèlves, Rosine Guimbaud
Topics & Concepts
Undifferentiated Pleomorphic SarcomaSarcomaMedicineMicrosatellite instabilityRhabdomyosarcomaLynch syndromeSoft tissue sarcomaMSH2ImmunohistochemistryPathologySoft tissuePathologicalOncologyInternal medicineDNA mismatch repairCancerBiologyGeneMicrosatelliteBiochemistryAlleleColorectal cancerGenetic factors in colorectal cancerSarcoma Diagnosis and TreatmentMetastasis and carcinoma case studies