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Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target

Haikel Dridi, Alexander Kushnir, Ran Zalk, Qi Yuan, Zephan Melville, Andrew R. Marks

2020Nature Reviews Cardiology219 citationsDOIOpen Access PDF

Topics & Concepts

Ryanodine receptor 2Heart failureRyanodine receptorAtrial fibrillationEndoplasmic reticulumCalsequestrinInternal medicineIntracellularContractilityMedicineCardiologyCalcium in biologyCalciumChemistryCell biologyBiologyCardiac electrophysiology and arrhythmiasIon channel regulation and functionAtrial Fibrillation Management and Outcomes
Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target | Litcius