A disordered tether to iLID improves photoswitchable protein patterning on model membranes
Daniele Di Iorio, Johanna Bergmann, Sayuri L. Higashi, Arne Hoffmann, Seraphine V. Wegner
Abstract
. An engineered version of iLID, disiLID, with a disordered domain as a membrane tether improves the recruitment of Nano under blue light and the reversibility in the dark, which enables protein patterning on membranes with higher spatiotemporal precision.
Topics & Concepts
MembraneBiophysicsMaterials scienceNanotechnologyChemistryBiologyBiochemistryPhotoreceptor and optogenetics researchElectrowetting and Microfluidic TechnologiesAdvanced biosensing and bioanalysis techniques