Chemical Compounds and Biologic Activities: A Review of Cedrela Genus
Thalya Soares Ribeiro Nogueira, Michel de Souza Passos, Lara Pessanha Soares Nascimento, Mayara Barreto de Souza Arantes, Noemi Oliveira Monteiro, Samyra Imad da Silva Boeno, Almir de Carvalho, Otoniel de Aquino Azevedo, Wagner da Silva Terra, Milena Gonçalves Curcino Vieira, Raimundo Braz‐Filho, Ivo José Curcino Vieira
Abstract
The genus Cedrela P. Browne, which belongs to the Meliaceae family, has eighteen species. Trees of this genus are of economic interest due to wood quality, as well as being the focus of studies because of relevant biologic activities as in other Meliaceae species. These activities are mainly related to limonoids, a characteristic class of compounds in this family. Therefore, the aim of this review is to perform a survey of the citations in the literature on the Cedrela genus species. Articles were found on quantitative and qualitative phytochemical studies of the Cedrela species, revealing the chemical compounds identified, such as aliphatics acid and alcohol, flavonoids, tocopherol, monoterpenes, sesquiterpenes, triterpenes, cycloartanes, steroids, and limonoids. Although some activities were tested, the majority of studies focused on the insecticidal, antifeedant, or insect growth inhibitor activities of this genus. Nonetheless, the most promising activities were related to their antimalarial and antitripanocidal effects, although further investigations are still needed.