CD74 promotes perineural invasion of cancer cells and mediates neuroplasticity via the AKT/EGR-1/GDNF axis in pancreatic ductal adenocarcinoma
Junfeng Zhang, Ling‐Ye Tao, Minwei Yang, Dapeng Xu, Shu‐Heng Jiang, Xueliang Fu, Dejun Liu, Yan‐Miao Huo, Wei Liu, Jian‐Yu Yang, Rong Hua, Ping Lu, Yongwei Sun
Topics & Concepts
Glial cell line-derived neurotrophic factorPancreatic cancerCancer researchPerineural invasionDownregulation and upregulationProtein kinase BNeurotrophic factorsGDNF family of ligandsCD74Gentamicin protection assayBiologyCancerChemistryMedicineInternal medicineCell biologyMetastasisSignal transductionImmunologyReceptorMajor histocompatibility complexMHC class IAntigenBiochemistryGeneMacrophage Migration Inhibitory FactorPancreatic and Hepatic Oncology ResearchNeuroblastoma Research and Treatments