Microwave-assisted synthesis of a zirconium-based MOF as an efficient catalyst for one-pot synthesis of xanthene derivatives: <i>in silico</i> study as a potential anti-HIV RNA
Mohammed S. Alsalhi, Mahmoud Tarek, Gehad E. Said, Abdulrahman A. Almehizia, Ahmed M. Naglah, Tamer K. Khatab
Abstract
, further indicating a promising potential for anti-HIV drug design. These findings underscore the potential of Zr-MOF and xanthene derivatives as potent candidates for HIV treatment, surpassing the reference molecule in terms of binding strength.
Topics & Concepts
XantheneCatalysisZirconiumIn silicoChemistryOne-pot synthesisCombinatorial chemistryHuman immunodeficiency virus (HIV)Organic chemistryBiochemistryVirologyMedicineGeneMulticomponent Synthesis of HeterocyclesMetal-Organic Frameworks: Synthesis and ApplicationsSynthesis and biological activity