Modulation of p38 MAPK and Nrf2/HO-1/NLRP3 inflammasome signaling and pyroptosis outline the anti-neuroinflammatory and remyelinating characters of Clemastine in EAE rat model
Tarek K. Motawi, Shohda A. El‐Maraghy, Ahmed S. Kamel, Salma E. Said, Mona A. Kortam
Topics & Concepts
InflammasomeExperimental autoimmune encephalomyelitisMAPK/ERK pathwayp38 mitogen-activated protein kinasesMedicinePharmacologyLuxol fast blue stainImmunologySignal transductionMultiple sclerosisBiologyInflammationCentral nervous systemEndocrinologyCell biologyMyelinInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideSpondyloarthritis Studies and Treatments