Gentiopicroside ameliorates psoriasis-like skin lesions in mice via regulating the Keap1-Nrf2 pathway and inhibiting keratinocyte activation
Jing Ren, Xin Chen, Haoyu Wang, Tao Yang, K. Zhang, Shu-yue Lei, Ling Qi, Chunlan Feng, Rong Zhou, Zhou Hu, Wei Tang
Topics & Concepts
HaCaTPsoriasisKeratinocyteKEAP1ImiquimodInflammationMedicineImmune systemOxidative stressPharmacologyImmunologyCancer researchTranscription factorBiologyIn vitroInternal medicineBiochemistryGenePsoriasis: Treatment and PathogenesisDermatology and Skin DiseasesGenomics, phytochemicals, and oxidative stress