Litcius/Paper detail

Copper-Catalyzed Borylation and Silylation of Dichlorocyclobutenones

Yi-Sen Qian, Zi‐Lu Wang, Bing Jiang, Zhenyu Xiao, Yun‐He Xu

2023Organic Letters15 citationsDOI

Abstract

We report copper-catalyzed borylation and silylation of dichlorocyclobutenones, which furnish the boron-substituted and silicon - substituted polyfunctionalized cyclobutenones in high yields. The reactions proceed under mild reaction conditions, show broad substrate scope, and display high chemoselectivity. In addition, a series of transformations of the corresponding products has been realized.

Topics & Concepts

BorylationChemistrySilylationChemoselectivityCatalysisScope (computer science)Substrate (aquarium)CopperBoronSiliconOrganic chemistryCombinatorial chemistryArylProgramming languageAlkylOceanographyComputer scienceGeologyOrganoboron and organosilicon chemistryCatalytic Cross-Coupling ReactionsCyclopropane Reaction Mechanisms