Kahook Dual Blade Goniotomy vs iStent inject: Long-Term Results in Patients with Open-Angle Glaucoma
Thorsteinn S. Arnljots, Mario A. Economou
Abstract
Purpose: Efficacy and safety evaluation of Kahook Dual Blade (KDB) goniotomy vs iStent inject implantation. Materials and Methods: Retrospective study in patients that underwent goniotomy with KDB or iStent inject implantation, stand-alone or combined with cataract surgery. Main outcome parameters were intraocular pressure (IOP), number of glaucoma medications, proportion of eyes achieving > 20% IOP reduction and number of eyes with postoperative IOP < 19 mmHg at last follow-up. Results: A total of 29 patients (30 eyes) were included in the iStent inject group and 30 patients (32 eyes) in the KDB group. Mean follow-ups were 20.9± 6.5 (KDB-alone) to 29.5± 7.6 (phaco-iStent inject ) months. Pre- and post-operative IOPs were 22.2± 5.8 mmHg and 15.9± 4.3 mmHg ( P =0.004) in the KDB-alone, 24.2± 6.8 mmHg and 16.2± 6.7 mmHg ( P =0.001) in the phaco-KDB, 20.6± 5.4 mmHg and 20.9± 6.8 mmHg ( P =0.598) in the iStent inject -alone as well as 20.9± 5.5 mmHg and 15.6± 3.4 mmHg ( P =0.003) in the phaco-iStent inject subgroups. No major complications occurred. Conclusion: All KDB and iStent subgroups except the stand-alone iStent inject subgroup showed a clinically significant IOP-lowering effect as a stand-alone procedure or combined with cataract surgery. Goniotomy with KDB in this setting seems to offer an advantageous IOP reduction compared to iStent inject . Keywords: MIGS, iStent inject , Kahook Dual Blade, glaucoma surgery, goniotomy A Letter to the Editor has been published for this article.