Transcriptional Reactivation of Lignin Biosynthesis for the Heterologous Production of Etoposide Aglycone in <i>Nicotiana benthamiana</i>
Seung Yeon Kim, Diego L. Wengier, Carin J. Ragland, Elizabeth S. Sattely
Abstract
. Furthermore, our results highlight the engineering value of MYB85, an early switch in lignin biosynthesis, for on-demand modulation of monolignol flux and support the role of MYB46 as a master regulator of lignin polymer deposition.
Topics & Concepts
Nicotiana benthamianaPhenylpropanoidPodophyllumBiochemistryMetabolic engineeringMonolignolBiologyAglyconeBiosynthesisPodophyllotoxinCell biologyChemistryBotanyEnzymeGeneStereochemistryGlycosidePlant Gene Expression AnalysisPlant Parasitism and ResistanceBiochemical and biochemical processes