Agomelatine, a structural analog of melatonin, improves kidney dysfunction through regulating the AMPK/mTOR signaling pathway to promote autophagy in obese rats
Sasivimon Promsan, Laongdao Thongnak, Nattavadee Pengrattanachot, Nichakorn Phengpol, Prempree Sutthasupha, Anusorn Lungkaphin
Topics & Concepts
AgomelatineAutophagyEndocrinologyPI3K/AKT/mTOR pathwayInternal medicineMelatoninAMPKMedicineInsulin resistanceKidneyOxidative stressApoptosisChemistryInsulinProtein kinase AAntidepressantKinaseHippocampusBiochemistryDietary Effects on HealthAutophagy in Disease and TherapyAdvanced Glycation End Products research