Recent advances in DDR (DNA damage response) inhibitors for cancer therapy
Binbin Cheng, Wei Pan, Yi Xing, Yao Xiao, Jianjun Chen, Zheng Xu
Topics & Concepts
Synthetic lethalityOlaparibWee1DNA damageCHEK1DNA repairCancer researchCancerPoly ADP ribose polymeraseChemistryKinaseDNABiologyGeneticsCell cycleBiochemistryPolymeraseCell cycle checkpointCyclin-dependent kinase 1DNA Repair MechanismsPARP inhibition in cancer therapyCancer therapeutics and mechanisms