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Berbamine induced AMPK activation regulates mTOR/SREBP-1c axis and Nrf2/ARE pathway to allay lipid accumulation and oxidative stress in steatotic HepG2 cells

Ankita Sharma, Sumit Kr Anand, Neha Singh, Upendra N. Dwivedi, Poonam Kakkar

2020European Journal of Pharmacology55 citationsDOI

Topics & Concepts

AMPKFatty acid synthaseChemistryOxidative stressLipogenesisInternal medicineEndocrinologyPeroxisomeBeta oxidationLipid metabolismFatty acidProtein kinase ABiochemistryKinaseBiologyMedicineReceptorLiver Disease Diagnosis and TreatmentBerberine and alkaloids researchGinger and Zingiberaceae research
Berbamine induced AMPK activation regulates mTOR/SREBP-1c axis and Nrf2/ARE pathway to allay lipid accumulation and oxidative stress in steatotic HepG2 cells | Litcius