Au nanoparticle-functionalized HKUST-1 sensor for electrochemical determination of sulfanilamide and acetaminophen
Saisai Chen, Chaohai Wang, Mengran Wang, Linghui Pan, Dayong Xu, Jiansheng Li
Abstract
Metal organic frameworks (MOFs) have been developed as a type of ideal electrode substrates for electrochemical sensing owing to their unique physicochemical properties . The improvement of their stability, sensitivity, signal-conversion capability, and universality of the related electrochemical sensors is the key to rapidly determinate contaminants. In this work, Au nanoparticles were introduced to prepare N-HKUST-1/Au composite to enhance conductivity and sensitivity of HKUST-1 modified material during electrochemical determination process. The introduction of exogenous Au materials increased the conductivity and electrochemical active area of N-HKUST-1, which in turn led to the broadening of the maximum detection concentration of SA to 251.6 μM. Meanwhile, N-HKUST-1/Au composite sensor for the determination of AP also exhibited excellent analytical performance with a detection range of 1–4448.4 μM and LOD of 0.16 μM. Furthermore, the recovery experiment at different concentration levels were conducted in practical water samples, the developed N-HKUST-1/Au composite sensor exhibits relatively satisfactory recoveries, indicating promising application in quantitative detection of SA and AP molecules.