ADME properties, bioactivity and molecular docking studies of 4-amino-chalcone derivatives: new analogues for the treatment of Alzheimer, glaucoma and epileptic diseases
Meliha Burcu Gürdere, Yakup Budak, Ümit M. Koçyiğit, Parham Taslımı, Burak Tüzün, Mustafa Ceylan
Topics & Concepts
Carbonic anhydraseChalconeAcetylcholinesteraseADMEProtein Data Bank (RCSB PDB)ChemistryCarbonic anhydrase IIEnzymeIsozymeStereochemistryBiochemistryIn vitroEnzyme function and inhibitionCholinesterase and Neurodegenerative DiseasesPhosphodiesterase function and regulation