Litcius/Paper detail

<i>Deep Survival Machines</i>: Fully Parametric Survival Regression and Representation Learning for Censored Data With Competing Risks

Chirag Nagpal, Xinyu Li, Artur Dubrawski

2021IEEE Journal of Biomedical and Health Informatics136 citationsDOI

Abstract

We describe a new approach to estimating relative risks in time-to-event prediction problems with censored data in a fully parametric manner. Our approach does not require making strong assumptions of constant proportional hazards of the underlying survival distribution, as required by the Cox-proportional hazard model. By jointly learning deep nonlinear representations of the input covariates, we demonstrate the benefits of our approach when used to estimate survival risks through extensive experimentation on multiple real world datasets with different levels of censoring. We further demonstrate advantages of our model in the competing risks scenario. To the best of our knowledge, this is the first work involving fully parametric estimation of survival times with competing risks in the presence of censoring.

Topics & Concepts

Censoring (clinical trials)CovariateComputer scienceProportional hazards modelParametric statisticsSurvival analysisParametric modelHazardRegressionEconometricsAccelerated failure time modelArtificial intelligenceStatisticsMachine learningData miningMathematicsOrganic chemistryChemistryStatistical Methods and InferenceGaussian Processes and Bayesian InferenceExplainable Artificial Intelligence (XAI)