Litcius/Paper detail

Disease spreading modeling and analysis: a survey

Pietro Hiram Guzzi, Francesco Petrizzelli, Tommaso Mazza

2022Briefings in Bioinformatics45 citationsDOI

Abstract

MOTIVATION: The control of the diffusion of diseases is a critical subject of a broad research area, which involves both clinical and political aspects. It makes wide use of computational tools, such as ordinary differential equations, stochastic simulation frameworks and graph theory, and interaction data, from molecular to social granularity levels, to model the ways diseases arise and spread. The coronavirus disease 2019 (COVID-19) is a perfect testbench example to show how these models may help avoid severe lockdown by suggesting, for instance, the best strategies of vaccine prioritization. RESULTS: Here, we focus on and discuss some graph-based epidemiological models and show how their use may significantly improve the disease spreading control. We offer some examples related to the recent COVID-19 pandemic and discuss how to generalize them to other diseases.

Topics & Concepts

DiseaseComputer scienceData scienceMedicinePathologyCOVID-19 epidemiological studiesComplex Network Analysis TechniquesOpinion Dynamics and Social Influence