Glycemic Variability in Diabetes Increases the Severity of Influenza
Rebecca J Marshall, Pornthida Armart, Katina D. Hulme, Keng Yih Chew, Alexandra C. Brown, Philip M. Hansbro, Conor J. Bloxham, Melanie S. Flint, Katharina Ronacher, Helle Bielefeldt‐Ohmann, Linda A. Gallo, Kirsty R. Short
Abstract
Every winter, people with diabetes are at increased risk of severe influenza. At present, the mechanisms that cause this increased susceptibility are unclear. Here, we show that the fluctuations in blood glucose levels common in people with diabetes are associated with severe influenza. These data suggest that glycemic stability could become a greater clinical priority for patients with diabetes during outbreaks of influenza.
Topics & Concepts
Diabetes mellitusGlycemicMedicineOutbreakInternal medicineIntensive care medicineVirologyEndocrinologyDiabetes and associated disordersDiabetes Management and ResearchPancreatic function and diabetes