Quantification of neurotransmitters in microdialysate samples following quetiapine dosing to schizophrenia phenotyped rats using a validated LC-MS/MS method
Fernando Carreño, Victória Etges Helfer, Keli Jaqueline Staudt, Laura Ben Olivo, Fabiano Barreto, Ana Paula Herrmann, Stela Maris Kuze Rates, Teresa Dalla Costa
Topics & Concepts
ChemistryChromatographyHomovanillic acidMonoamine neurotransmitterAtypical antipsychoticDerivatizationDetection limitSolid phase extractionSerotoninMass spectrometryPharmacologyAntipsychoticSchizophrenia (object-oriented programming)BiochemistryPsychologyPsychiatryReceptorMedicineNeurotransmitter Receptor Influence on BehaviorSchizophrenia research and treatmentReceptor Mechanisms and Signaling