Risk Factors for Carbapenem-Resistant <i>Enterobacterales</i> Clinical Treatment Failure
Nicholas Rebold, Abdalhamid M Lagnf, Sara Alosaimy, Dana Holger, Paige Witucki, Andrew Mannino, Michelle Dierker, Kristen Lucas, Ashlan J. Kunz Coyne, Amer El Ghali, Kaylee E Caniff, Michael P. Veve, Michael J. Rybak
Abstract
(CRE) infections using patient, clinical, and treatment variables to understand which characteristics are associated with the highest risk of clinical failure. Knowing which risk factors are associated with CRE infection failure can provide clinicians better prognostic and targeted interventions. Research can also further investigate why certain risk factors cause more clinical failure and can help develop treatment strategies to mitigate associated risk factors.
Topics & Concepts
MedicineOdds ratioInternal medicineBacteremiaCarbapenemRetrospective cohort studyConfidence intervalDialysisAntibioticsIntensive care medicineCarbapenem-resistant enterobacteriaceaeKlebsiella pneumoniaeMicrobiologyGeneChemistryEscherichia coliBiochemistryBiologyAntibiotic Resistance in BacteriaAntibiotic Use and ResistanceAntibiotics Pharmacokinetics and Efficacy