TsCl-promoted thiolation of quinoline <i>N</i>-oxides with thiophenols
Chengxian Hu, Ruikai Liu, Zhitao Ning, Dan Mou, Ying Fu, Zhengyin Du
Abstract
-toluenesulfonyl chloride-assisted tandem C-H bond activation, nucleophilic addition, deoxygenation and aromatization processes. This method does not require the use of metal catalysts and oxidants. It shows the advantages of wide functional group tolerance, short reaction times and simple operation.
Topics & Concepts
QuinolineChemistryChlorideMetalCatalysisInorganic chemistryOrganic chemistrySulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods