Yap Expression Is Closely Related to Tumor Angiogenesis and Poor Prognosis in Hepatoblastoma
Wenchen Gong, Zhiqiang Han, Feng Fang, Lu Chen
Abstract
In hepatoblastoma, YAP may promote VEGF induced angiogenesis and metastases, with resulting poorer prognosis, representing a potential adverse prognostic marker.
Topics & Concepts
HepatoblastomaMedicineAngiogenesisImmunohistochemistryMetastasisPathologyOncologyCancer researchInternal medicineCancerHippo pathway signaling and YAP/TAZLipid metabolism and biosynthesisUbiquitin and proteasome pathways