A covalent organic framework-based nanoreactor for enhanced chemodynamic therapy through cascaded Fenton-like reactions and nitric oxide delivery
Tian Song, Jin-Zhou Lv, Bo Wang, Wenyan Li, B. Ge, Yanan Li, Yu‐Bin Dong
Abstract
a stepwise post-synthetic modification. The obtained CuO2@COF-SNO can undergo a cascade reaction in the tumor microenvironment to generate reactive oxygen and nitrogen species (ROS/RNS) to enhance chemodynamic therapy of the tumor.
Topics & Concepts
NanoreactorNitric oxideChemistryCovalent bondFenton reactionChemiluminescenceOxidePhotochemistryCombinatorial chemistryRadicalCatalysisBiochemistryOrganic chemistryNanoplatforms for cancer theranosticsCovalent Organic Framework ApplicationsMetal-Organic Frameworks: Synthesis and Applications