The omentum, a niche for premetastatic ovarian cancer
Xiaojing Ma
Abstract
The work by Etzerodt et al. in this issue of JEM (https://doi.org/10.1084/jem.20191869) identifies a distinct omentum-resident macrophage population of embryonic origin and demonstrates that these cells provide a niche for ovarian cancer metastasis and cancer stemness. This research opens up for many questions and therapeutic prospects.
Topics & Concepts
Ovarian cancerNicheMetastasisBiologyPopulationCancer researchCancerMedicineGeneticsEcologyEnvironmental healthCancer Mechanisms and TherapyMetastasis and carcinoma case studiesCircular RNAs in diseases