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‘The cure for us is a lot of things’: How young people with <scp>Prader‐Willi</scp> syndrome view themselves and future clinical trials

Elisabeth M. Dykens, Elizabeth Roof, Hailee Hunt‐Hawkins

2021Journal of Applied Research in Intellectual Disabilities15 citationsDOI

Abstract

BACKGROUND: Despite work on the self-identities of people with intellectual disabilities, research has yet to describe the self-perceptions of people with Prader-Willi syndrome (PWS). The perspectives of those with PWS are also important for rapidly evolving clinical trials aimed at treating symptoms of PWS. METHOD: Twenty-one young people with PWS were administered a semi-structured interview that assessed how they perceive their syndrome and clinical trials. Transcribed interviews were reliably coded using content-driven, applied thematic analyses. RESULTS: Five themes emerged: struggles with chronic hunger and food-seeking that impede goals and relationships; struggles with anxiety and outbursts, schedule changes and school; distancing from PWS; needs for clinical trials that cure PWS, reduce hunger or anxiety, and lead to improved outcomes; and needs for advocacy and awareness of PWS. CONCLUSIONS: Findings shed new light on the self-perceptions of those with PWS and have important implications for current interventions and future clinical trials.

Topics & Concepts

Thematic analysisClinical trialAnxietyDistancingPerceptionPsychological interventionPsychologyMedicineClinical psychologyQualitative researchDevelopmental psychologyPsychiatryDiseaseCoronavirus disease 2019 (COVID-19)Infectious disease (medical specialty)NeuroscienceSociologySocial sciencePathologyGenetic Syndromes and ImprintingWilliams Syndrome ResearchChild Nutrition and Feeding Issues
‘The cure for us is a lot of things’: How young people with <scp>Prader‐Willi</scp> syndrome view themselves and future clinical trials | Litcius