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Smad3 regulates smooth muscle cell fate and mediates adverse remodeling and calcification of the atherosclerotic plaque

Paul Cheng, Robert Wirka, Juyong Brian Kim, Hyun-Jung Kim, Trieu Nguyen, Ramendra Kundu, Quanyi Zhao, Disha Sharma, Albert J Pedroza, Manabu Nagao, Dharini Iyer, Michael P. Fischbein, Thomas Quertermous

2022Nature Cardiovascular Research62 citationsDOIOpen Access PDF

Topics & Concepts

PhenotypeCalcificationBiologyVascular smooth muscleTranscriptomePopulationCell biologyCellPathologyGene expressionGeneEndocrinologyMedicineSmooth muscleGeneticsEnvironmental healthCongenital heart defects researchTGF-β signaling in diseasesGenetic factors in colorectal cancer
Smad3 regulates smooth muscle cell fate and mediates adverse remodeling and calcification of the atherosclerotic plaque | Litcius