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Dexmedetomidine suppresses hippocampal astrocyte pyroptosis in cerebral hypoxic-ischemic neonatal rats by upregulating microRNA-148a-3p to inactivate the STAT/JMJD3 axis

Yi Zhong, Shengzhao Wang, Yongqiang Yin, Jialu Yu, Yang Liu, Hong Gao

2023International Immunopharmacology24 citationsDOI

Topics & Concepts

PyroptosisNeuroprotectionAstrocytePharmacologyHippocampal formationGene knockdownApoptosisBiologyChemistryEndocrinologyProgrammed cell deathBiochemistryCentral nervous systemInflammasome and immune disordersNeonatal and fetal brain pathologyAnesthesia and Neurotoxicity Research
Dexmedetomidine suppresses hippocampal astrocyte pyroptosis in cerebral hypoxic-ischemic neonatal rats by upregulating microRNA-148a-3p to inactivate the STAT/JMJD3 axis | Litcius