Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
Zhifeng Zou, Lei Yang, Hui‐Jun Nie, Jing Gao, Shumin Lei, Yi Lai, Fan Zhang, Ernst Wagner, Haijun Yu, Xiaohua Chen, Zhiai Xu
Topics & Concepts
ProdrugProtein degradationCereblonCancer researchPharmacologyTargeted therapyCancerMedicineChemistryUbiquitinUbiquitin ligaseBiochemistryInternal medicineGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments