A bi-layered scaffold of a poly(lactic-<i>co</i>-glycolic acid) nanofiber mat and an alginate–gelatin hydrogel for wound healing
Wendi Ma, Mingjuan Zhou, Wenying Dong, Shanshan Zhao, Yilong Wang, Jihang Yao, Zhewen Liu, Hongshuang Han, Dahui Sun, Mei Zhang
Abstract
experiment using a Sprague-Dawley (SD) rat skin wound as a model showed that the RBS could accelerate the wound healing rate compared with the Res-PLGA group and ADA4-GEL6 group. These results indicated that this resveratrol-loaded bi-layered scaffold can be a potential candidate in promoting wound healing.
Topics & Concepts
Glycolic acidGelatinMaterials scienceHaCaTPLGANanofiberWound healingDermisResveratrolElectrospinningScaffoldBiomedical engineeringLactic acidChemical engineeringComposite materialNanotechnologyChemistrySurgeryIn vitroOrganic chemistryPolymerAnatomyBiochemistryNanoparticleMedicineBiologyEngineeringBacteriaGeneticsWound Healing and TreatmentsElectrospun Nanofibers in Biomedical ApplicationsSilk-based biomaterials and applications